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Depression, anxiety and loss of resilience after multiple traumas: an illustration of a mediated moderation model of sensitization in a group of children who survived the Nazi Holocaust

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dc.contributor.author Fossion, Pierre
dc.contributor.author Leys, Christophe
dc.contributor.author Kempenaers, Chantal
dc.contributor.author Braun, Stephanie
dc.contributor.author Verbanck, Paul
dc.contributor.author Linkowski, Paul
dc.date.accessioned 2015-03-14T08:39:54Z
dc.date.available 2015-03-14T08:39:54Z
dc.date.issued 2013
dc.identifier.citation Journal of Affective Disorders
dc.identifier.issn 0165-0327
dc.identifier.uri http://www.sciencedirect.com/science/article/pii/S016503271300640X
dc.identifier.uri http://evidence.thinkportal.org/handle/123456789/100
dc.description.abstract Depressive and anxiety disorders (DAD) have become a major public health problem. Multiple trauma is known to increase the risk of DAD through a sensitization mechanism. We investigate the hypothesis that resilience is a mediator of this mechanism. Former Hidden Children (FHC), the Jewish youths who spent World War II in various hideaway shelters across Nazi-occupied Europe, were compared with a control group. In each group, we measured the presence of multiple traumas, the resilience with the Resilience Scale for Adults, which has a six factors solution, and the DAD with the Hopkins Symptoms Checklist. We test a mediated moderation model with childhood trauma as the predictor; Later trauma as the moderator; Resilience as the mediator; and DAD as the outcome variable. Results are consistent with a sensitization model of DAD mediated by resilience: confrontation with a primary trauma during childhood followed by secondary trauma(s) after childhood damages resilience, which, in turn, results in higher level of DAD. We are unable to differentiate if the sensitization process is a consequence of the nature of the trauma endured by FHC (long-standing exposure to extreme external events) or a consequence of the fact that this first trauma occurred during childhood. Resilience construct is multi-factorial and a limited damaging of some of the factors is sufficient to lead to DAD even if other factors remain unaltered. Resilience can be altered by multiple traumas and, therefore, needs to be bolstered in therapy sessions.
dc.subject Depression
dc.subject Holocaust
dc.subject Resilience
dc.subject Stress
dc.subject Trauma
dc.title Depression, anxiety and loss of resilience after multiple traumas: an illustration of a mediated moderation model of sensitization in a group of children who survived the Nazi Holocaust
dc.type Article


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