A systematic review of the effects of repeated painful procedures in infants: Is there a potential to mitigate future pain responsivity?

dc.creator	Linda A. Hatfield
dc.creator	Margaret A. Meyers
dc.creator	Theresa M. Messing
dc.date	2013-01-01T00:00:00Z
dc.date.accessioned	2015-07-20T22:15:46Z
dc.date.available	2015-07-20T22:15:46Z
dc.identifier	10.5430/jnep.v3n8p99
dc.identifier	1925-4040
dc.identifier	1925-4059
dc.identifier	https://doaj.org/article/ca20092c05fd485992a5fb8d5d552f96
dc.identifier.uri	http://evidence.thinkportal.org/handle/123456789/17892
dc.description	<p class="a"><strong>Background:</strong> Multiple lines of evidence suggest repeated painful procedures early in life may permanently disrupt the developing central nervous system. Painful diagnostic, medical, and minor surgical procedures performed in the neonatal intensive care unit such as venipunctures, heel lances, immunizations, and central venous catheter insertion are a significant portion of painful events experienced by infants. The objective of this systematic review is to synthesize findings from published clinical trials evaluating the effect of repeated painful procedures experienced during the plasticity of the developing peripheral and central nervous system and their influence on future pain responsivity.</p> <p class="a"><strong>Methodology/Principal Findings:</strong> A systematic review of peer-refereed clinical trials was conducted. Clinical trials examining the effect of repeated painful procedures experienced during the plasticity of the developing peripheral and central nervous system and their influence on future pain responsivity were identified from electronic databases PUBMED, MEDLINE and CINAHL. Application of inclusion/exclusion criteria and limitations identified five clinical trials for critical reviewed. Findings suggest that repetitive pain experienced during a critical window of neuro-<br /> development alters the structure and function of an infant’s nervous system, influences subsequent pain responses through childhood and may contribute to the development of chronic pain.</p> <strong>Conclusions:</strong> Current research asserts that inadequate relief of infant pain and distress during tissue-damaging procedures may permanently decrease an individual’s pain tolerance, and increase pain responses later in life.
dc.language	English
dc.publisher	Sciedu Press
dc.relation	http://www.sciedu.ca/journal/index.php/jnep/article/view/1802
dc.relation	https://doaj.org/toc/1925-4040
dc.relation	https://doaj.org/toc/1925-4059
dc.source	Journal of Nursing Education and Practice, Vol 3, Iss 8 (2013)
dc.subject	Special aspects of education
dc.subject	LC8-6691
dc.subject	Education
dc.subject	L
dc.subject	DOAJ:Education
dc.subject	DOAJ:Social Sciences
dc.subject	Special aspects of education
dc.subject	LC8-6691
dc.subject	Education
dc.subject	L
dc.subject	DOAJ:Education
dc.subject	DOAJ:Social Sciences
dc.subject	Special aspects of education
dc.subject	LC8-6691
dc.subject	Education
dc.subject	L
dc.subject	Special aspects of education
dc.subject	LC8-6691
dc.subject	Education
dc.subject	L
dc.subject	Special aspects of education
dc.subject	LC8-6691
dc.subject	Education
dc.subject	L
dc.title	A systematic review of the effects of repeated painful procedures in infants: Is there a potential to mitigate future pain responsivity?
dc.type	article