The incidence of cardiovascular disease, cancer and type 2 diabetes comorbidities in HIV infection: A systematic review

dc.creator	Tilahun Nigatu
dc.creator	Brian Oldenburg
dc.creator	Julian Elliott
dc.creator	Geoffrey Setswe
dc.creator	Mulu Abraha Woldegiorgis
dc.date	2013-01-01T00:00:00Z
dc.date.accessioned	2015-08-12T11:21:12Z
dc.date.available	2015-08-12T11:21:12Z
dc.identifier	10.5430/jnep.v3n7p58
dc.identifier	1925-4040
dc.identifier	1925-4059
dc.identifier	https://doaj.org/article/905ad3c5e32842819a32ff643ba39347
dc.identifier.uri	http://evidence.thinkportal.org/handle/123456789/28785
dc.description	<p class="a"><strong>Introduction:</strong> Epidemiological linkages between HIV/AIDS and common Noncommunicable diseases are established. However, the incidence of these diseases among people living with HIV is not well examined.</p> <p class="a"><strong>Objectives:</strong> To describe the incidence of cardiovascular diseases, cancers, and type 2 diabetes among people living with HIV.</p> <p class="a"><strong>Methods:</strong> We have conducted a systematic review of incidence studies. Studies reporting on the incidence of cardio-<br /> vascular diseases, cancers and type 2 diabetes among People living with HIV were retrieved from Embase and Medline databases. We used explicit eligibility and quality appraisal criteria to screen and select studies. We extracted study characteristics, outcome values and key conclusions. Findings were reported using tables and narrative summaries.</p> <p class="a"><strong>Results:</strong> A total of 30 studies were included in this systematic review. The incidence of cardiovascular diseases, cancers, and type 2 Diabetes comorbidities among people living with HIV was found to range from 1.19 to 11.3, 6.63 to 43.77, and 4.42 to 36.26 per 1000 person years, respectively. HIV infection was associated with increased risk of cardiovascular diseases and cancers. Specific types of antiretroviral drugs and longer duration of antiretroviral treatment were among the determinants of cardiovascular diseases and type 2 Diabetes in HIV infection. While the introduction of antiretroviral treatment was followed by a rapid decline in the incidence of AIDS-defining cancers, its effect on the incidence of non-AIDS defining cancers looks minimal.</p> <strong>Conclusion:</strong> The current evidence suggests that policies and interventions targeting people living with HIV should prioritize the prevention of the risk of common Noncommunicable diseases together with the rapid scale up of HIV treatment.
dc.language	English
dc.publisher	Sciedu Press
dc.relation	http://www.sciedu.ca/journal/index.php/jnep/article/view/1640
dc.relation	https://doaj.org/toc/1925-4040
dc.relation	https://doaj.org/toc/1925-4059
dc.source	Journal of Nursing Education and Practice, Vol 3, Iss 7 (2013)
dc.subject	Special aspects of education
dc.subject	LC8-6691
dc.subject	Education
dc.subject	L
dc.subject	DOAJ:Education
dc.subject	DOAJ:Social Sciences
dc.subject	Special aspects of education
dc.subject	LC8-6691
dc.subject	Education
dc.subject	L
dc.subject	DOAJ:Education
dc.subject	DOAJ:Social Sciences
dc.subject	Special aspects of education
dc.subject	LC8-6691
dc.subject	Education
dc.subject	L
dc.subject	Special aspects of education
dc.subject	LC8-6691
dc.subject	Education
dc.subject	L
dc.subject	Special aspects of education
dc.subject	LC8-6691
dc.subject	Education
dc.subject	L
dc.title	The incidence of cardiovascular disease, cancer and type 2 diabetes comorbidities in HIV infection: A systematic review
dc.type	article