In this study, 1st grade technical high school students’ science process skill levels were determined and the relationships between science process skills levels and kind of the vocational school, age and gender were investigated. This study was carried out in 2006-2007 educational year, in six districts in Balıkesir, with 970 1st grade high school students from five kinds of vocational schools. The science process skill levels of the students from different vocational schools were compared. The effects of the attitude towards chemistry, the kind of the vocational school, age and gender were investigated. The results showed that the measured factors have significant effects on science process skill levels.