This research was carried out as a descriptive study in order to determine the anxiety levels of third and last year students of Ege University School of Nursing while preparing their thesis and the factors affecting this. The research was performed with 142 students from third and last year students studying at Ege University School of Nursing. Data was collected using a questionnaire prepared by the researchers and State-Trait Anxiety Inventory. It was determined that, 52,1% of the students were above the age of 23 years, 53,5% were last year students, 44,4% stayed in dormitory, 61,3% indicated that they experienced anxiety problems while determining the subject of thesis, and 38,7% got sufficient assistance from their supervisor. State anxiety average was 49,11± 12,23 and Trait anxiety average was 45,14± 7,8. Age groups, year of their study, staying with parents or receiving help from the supervisor were determined not to be effective in anxiety levels. Guiding and supporting attitudes of the teaching staff were thought to be helpful in increasing self-confidence of young people by reducing anxiety.