The algorithm of the research of the structural changes of the temporomandibular joint was based on comparative analysis of the history/anamnesis, clinical picture and the results of a three-dimensional computed tomography. It was found that among 235 patients who referred to the clinic the largest share of pathological TMJ dysfunction accounts is for the joint - 65.5% of cases, 24.5% of cases - arthrosis, arthritis, 8.8% - arthrosis and 1.2%, - ankylosis, respectively. When patients refer with myofascial pain dysfunctional syndrome that is less than 1.5 years from the beginning of the disease with timely treatment can prevent structural changes in the TMJ. For a complete diagnosis and adequate treatment of this disease, an integrated multidisciplinary approach should be done by the doctors of different dental profile.