This work examines how teaching and learning are transformed with the introduction of the Information and Communications Technologies (ICT’s), particularly using e-blended courses, implemented in the Faculties of Physics and Arts and Letters of the Havana University. Some of the collaborative activities are described using the interactive platform Moodle, like Forum, the electronic Portfolio or e-portfolio, and WebQuest. An example of the instrumentation of WebQuest is presented in a topic of the course of Modern Physics II, allowing to appreciate the advantages offered. Thus, increasing the motivation and activating the student's learning when they face a real problem posed by WebQuest.